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Clenbuterol - Magnus Pharmaceuticals

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Clenbuterol - Magnus Pharmaceuticals

20.36 £

Even though not a magical fat loss substance, Clenbuterol is an excellent thermogenic. You will still need to burn more calories than you take in if you are going to lose body fat, but Clen will help you burn calories at a higher rate. While it can help you lose body fat at an accelerated rate, especially that last little bit of stubborn body fat, responsible use remains imperative.
Clenbuterol_Magnus_Pharmaceuticals_Leaflet.pdf (39.18kB)

Active substanceClenbuterol Hydrochloride
Dose for men20-80mcg/day
Dose for women20-80mcg/day
Active life36 hours
Contents100 x 40mcg tablets

About Clenbuterol
Beyond treating breathing disorders, Clenbuterol is commonly used as a thermogenic. In fact, you will more than likely find more Clenbuterol use in fat loss plans than anywhere else. It is a very common fat burning tool used by many anabolic steroid users. It is a long standing favorite among competitive bodybuilders and other physique athletes during contest preparation. However, it is also used by non-steroid users for its fat loss properties. You do not have to use anabolic steroids to use this compound for fat loss.

Clenbuterol hydrochloride is an anti-asthma medication that belongs to a broad group of drugs knows as sympathomimetics. These drugs affect that sympathetic nervous system in a wide number of ways, largely mediated by the distribution of adrenoceptors. There are actually nine different types of these receptors in the body, which are classified as either alpha or beta and further subcategorized by type number. Depending on the specific affinities of these agents for the various receptors, they can potentially be used in the treatment of conditions such as asthma, hypertension, cardiovascular shock, arrhythmias, migraine headaches and anaphylactic shock. The text Goodman and Gillman's The Pharmacological Basis of Therapeutics 9th edition does a good job of describing the diverse nature in which these drugs affect the body.

Most of the actions of catecholamines and sympathomimetic agents can be classified into seven broad types: (1) peripheral excitatory action on certain types of smooth muscles such as those in blood vessels supplying the skin, kidney, and mucous membranes, and on the gland cells, such as those of the salivary and sweat glands; (2) a peripheral inhibitory action on certain other types of smooth muscle, such as those in the wall of the gut, in the bronchial tree, and in blood vessels supplying skeletal muscle; (3) a cardiac excitatory action, responsible for an increase in heart rate and force of contraction; (4) metabolic actions, such as an increase in the rate of glycogenolysis in liver and muscle and liberation of free fatty acids from adipose tissue; (5) endocrine actions, such as modulation of the secretion of insulin, rennin, and pituitary hormones; (6) CNS actions, such as respiratory stimulation and, with some of the drugs, an increase in wakefulness and psychomotor activity and a reduction in appetite; and (7) presynaptic actions that result in either inhibition or facilitation of the release of the neurotransmitters such as such as norepinephrine and acetylcholine.

Clenbuterol hydrochloride is specifically a selective beta-2 sympathomimetic, primarily affecting only one of the three subsets of beta-receptors. Of particular interest is the fact that this drug has little beta-1 stimulating activity. Since beta-1 receptors are closely tied to the cardiac effects of these agents, this allows clenbuterol hydrochloride to reduce reversible airway obstruction (an effect of beta-2 stimulation) with much less cardiovascular side effects compared to non-selective beta agonists. Clinical studies with this drug show it is extremely effective as a bronchodilator, with a low level of user complaints and high patient compliance . Clenbuterol hydrochloride also exhibits an extremely long half-life in the body, which is measured to be approximately 34 hours long . This makes steady blood levels easy to achieve, requiring only a single or twice daily dosing schedule at most . This of course makes it much easier for the patient to use, and may tie in to its high compliance rate.

In animal studies clenbuterol hydrochloride is shown to exhibit anabolic activity, obviously an attractive trait to a bodybuilder or athlete. This compound is additionally a known thermogenic , with beta-2 agonists like clenbuterol hydrochloride shown to directly stimulate thermogenic , with beta-2 agonists like clenbuterol hydrochloride shown to directly stimulate fat cells and accelerate the breakdown of triglycerides to form free fatty acids. Its efficacy in this area makes clenbuterol hydrochloride a very popular fat loss drug among the bodybuilding community. Those interested in this drug are often hoping it will produce a little of both benefits, promoting the loss of body fat while imparting increases in strength and muscle mass. But as was well pointed out by a review published in the August 1995 issue of Medicine and Science in Sports and Exercise, the possible anabolic results in humans are very questionable, and based only on animal data using much larger doses than would be required for bronchodilation. With such reports there has been a lot of debate as to whether or not clenbuterol hydrochloride is really anabolic in humans at all. Some seem to swear by the fact that it builds muscle, and use clenbuterol hydrochloride regularly as an off-season or adjunct anabolic. To others, the MSSE report is confirmation that athletes have wasted valuable time and money on drugs that do not build muscle. The debate over clenbuterol hydrochloride's potential anabolic activity continues today.

Clenbuterol effects
As a thermogenic, the effects of Clenbuterol are very simple. As the body temperature increases, the individual is able to burn calories at an enhanced rate. Body temperature goes up, the metabolism is enhanced, fat cells are stimulated, the breakdown of triglycerides is enhanced and fat loss occurs.

While Clenbuterol is a powerful fat loss agent, it won't make a fat physique lean on its own. You still have to diet in order to lose body fat, and if you don't, no fat loss will occur. If you are obese or significantly overweight, it's best to skip Clenbuterol until you are a little leaner. The best time to use Clenbuterol is once you're already fairly lean in an effort to help you rid that last little body fat.

Due to Clenbuterol being best served for final touches in a fat loss plan, this is why you'll see it in many physique based plans such as bodybuilding, figure and fitness endeavours. It's commonly used the last 8-10 weeks leading up to a competition, sometimes a little longer, but regardless of the specific time frame the individual is normally already fairly lean.

Clenbuterol administration
In a performance setting as a thermogenic, Clenbuterol doses will start low and generally increase overtime. Most men will find starting at 40mcg per day to be perfect. Many women may also be fine with this starting dose, but many will be far more comfortable with a starting dose of 20mcg per day. As the body adapts, the dose will need to increase in order to maintain the full fat loss benefits. There are three different approaches on how and when to use Clenbuterol:

Two week rotation
One of the most common methods of Clenbuterol for fat loss purposes is two weeks on followed by two weeks off. This type of use will normally continue until the end goal is reached. The individual will start with the initial dose and increase it by 20mcg every few days until he has reached the maximum desired dose. The individual will then hold at this dose the final days of the two week period and then discontinue all Clenbuterol use for two weeks. At the end of the two weeks with no Clen, the individual will begin the process again.

Continuous use
Due to the body's ability to adapt to Clenbuterol, continuous use is very hard, however it can work very well. The individual will begin with the starting dose of 20-40mcg per day and hold at that dose for 2-3 weeks. At the end of the 2-3 week period, the individual will increase the dose by 20mcg and hold at that dose for another 2-3 weeks. From here, the individual will increase the dose 20mcg every 2-3 weeks as needed until the diet or total Clen use comes to an end.

In between
The final preferred method of Clenbuterol use lasts for 4-6 weeks and can be an excellent way to use it for the individual who is only using it the last few weeks leading up to competition. The individual will start with 40mcg per day and increase periodically until he reaches the maximum desired dose and will hold at the maximum dose the final 7-14 days of the plan. The increases in dosing will not be as dramatic as the two week rotation schedule but stronger than the continuous plan. At this stage, if more Clen is still needed, the individual will need to wait 4-6 weeks before beginning a new phase.

Regardless of the type of schedule you use, the maximum Clenbuterol dose will normally be 120mcg per day. Some may find 140mcg per day to be acceptable, especially some men, but no one should for any reason surpass the 140mcg per day mark if they are going to avoid cardiac damage. Regardless of the plan, Clenbuterol use should be kept at no more than 16 weeks of total use. 16 weeks of total use per year should be your guide.

Clenbuterol side effects
The side effects of Clenbuterol can be very strong and annoying, and they will generally affect most people in one way or another. The most common side effects surround a jittery or wired feeling, shaky hands and increased sweating. Most all who use Clenbuterol will experience such effects to a degree.

As with many stimulating substances, some will experience headaches as well as possible nausea. One of the more bothersome possible side effects of Clenbuterol Hydrochloride will be muscle cramps. Staying well hydrated is often enough to avoid or remedy this problem, but supplementing with taurine can also help. Clenbuterol has been shown to deplete taurine, so supplementation may be necessary for some. Some may also have issues with insomnia. Clenbuterol has an active half-life that stretches to the 34 hour mark, and that can make sleep impossible for some people. Many will, however, find if they take their Clenbuterol first thing in the morning they will not have any issues with sleep, but due to the long half-life some will find insomnia occurs regardless of when they take it.

The severe side effects of Clenbuterol include high blood pressure, irregular heartbeat, trembling and even panic. Some studies have also shown that Clenbuterol abuse can also lead to cardiac hypertrophy, which could potentially lead to death. It is very possible to use this compound without such effects, but as with so many things in life it will require responsible use and a thorough understanding of Clenbuterol.