Ligandrol LGD-4033 - Magnus Pharmaceuticals
Ligandrol LGD-4033 - Magnus Pharmaceuticals
|Ligandrol is often said to be the strongest most effective SARM. If you were to try a SARM this would be the one to pick and more than likely the one you always pick regardless if using one or more SARM's at a time. Bulking, cutting, strength, endurance, and recovery – this SARM provides everything an athlete, bodybuilder or simply someone looking to get in shape could want. What will the specific results be? It's impossible to say; genetic response (positive benefits) with SARM's as is with steroids is highly dependent on just that, genetic response. Train smart, eat right and this product should provide a nice boost without horrific effects.
|Active substance||Ligandrol LGD-4033|
|Dose for men||10mg / day (6-12 weeks)|
|Active life||30 hours|
|Contents||50 x 10mg capsules|
LGD-4033, better known as Ligandrol is a Selective Androgen Receptor Modulator (SARM) that like testosterone is anabolic but without the effects that display significantly outside muscle tissue. Ligand Pharmaceuticals, ligand, referring to functional binding molecules, developed LGD-4033. Ligand Pharmaceuticals has made a name for itself with SARM research along with GTx, the two representing the bulk of SARM creation over the past decade.
Ligandrol is a SARM that binds tightly to the androgen receptors, primarily those of muscle and bone. Attaching to the androgen receptors, this creates enhanced anabolic activity in the body (muscle building) and has also been shown to be anti-catabolic (muscle wasting).
FreeStudies have shown Ligandrol to hold significant effects on bone deterioration through a strengthening effect. Along with its muscle building and bone strengthening properties, unlike anabolic steroids that attach to the androgen receptor, there is no activity presented outside the target muscle and bone areas of the body or at least only minimally.
The effects of Ligandrol can range from bulking and cutting to total body transformation. It is hard to compare the power of Ligandrol to various anabolic steroids due to SARM's still being relatively new to the market, but the effects do appear to be strong. Off-season or bulking athletes can expect to gain significant strength and muscle mass with adequate calories. They will also find water retention cannot occur, meaning any weight gained will be that of lean muscle tissue.
For the dieting or cutting athlete, one of the primary concerns is protecting lean muscle mass. When you want to lose fat, you must burn more calories than you consume, and this can and will lead to muscle tissue loss without protective agents. Regardless of how genetically superior an individual is, some muscle tissue loss is unavoidable. By increasing anabolic activity, such as attaching a potent SARM to the body, muscle tissue can be preserved. This will result in a tighter, leaner, harder and more muscular physique. Some data, although rudimentary at this stage has shown the effects of Ligandrol may also, to a degree, promote fat loss.
Increases in muscular endurance are also reported, especially when stacked with other SARMs. It is unclear how much of an effect Ligandrol will have on endurance when used alone.
Ligandrol (LGD-4033) carries a half-life of approximately 30 hours and is best taken once daily. 10mg per day is the most common dose with some
going as high as 20mg per day with little to no complications. Ligandrol can be stacked with other SARMs such as Ostarine (MK 2866) or Endurobol (GW-50156).
Ligandrol side effects
The side effects of Ligandrol appear to be minimal and often non-existent in many users. Unlike anabolic steroids that promote large amounts of androgenic activity, such related negative effects appear to be absent in most all cases. Side effects of Ligandrol are possible, but again very rare, making it one of the more desirable items in the performance enhancement arsenal.
The side effects of Ligandrol do not include any of an estrogenic nature, making water retention, bloating, gynecomastia and high blood pressure associated with water retention impossible. LGD-4033 does not promote aromatization, the conversion of testosterone to estrogen. No anti-estrogens are needed with the use of this SARM.
Despite an attachment to the androgen receptors, the target area remains muscle and bone. Acne and hair loss cannot occur with this SARM. The side effects of Ligandrol should also not be concerning to the prostate; some activity in the prostate may exist, but should be insignificant. Virilization, the masculine traits often promoted in women due to the use of anabolic steroids should not occur with this SARM.
No negative effects on the cardiovascular system have been reported, such as negative effects on cholesterol or blood pressure.
Testosterone suppression is possible but should not be as significant as suppression related to anabolic steroid use. Some claim suppression is suppression regardless of the rate, but that's simplistic at best. A man with natural testosterone levels of 650 ng/dl who is suppressed to 450 ng/dl, that is a far cry from 42 ng/dl. More importantly, data has shown Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) will both remain at their current state. Some data has also shown slight decreases in Sex Hormone Binding Globulin (SHBG), which in turn may increase Free testosterone levels. However, a significant increase in Free testosterone is unlikely. Post Cycle Therapy (PCT) medications may or may not be needed depending on the individual, but some period of normalization is generally required.
Although taken orally, LGD-4033 is not toxic to the liver and should have no affect on liver enzymes. This product does not belong to the C17-alpha alkylated (C17-aa) or methylated class of medications.